Genetic and biological markers in drug abuse and alcoholism
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Genetic and biological markers in drug abuse and alcoholism

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Published by Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, For sale by the Supt. of Docs., U.S. G.P.O. in Rockville, Md, Washington, D.C .
Written in English

Subjects:

  • Drug abuse,
  • Alcoholism -- Genetic aspects,
  • Biochemical markers

Book details:

Edition Notes

Statementeditors, Monique C. Braude, Helen M. Chao
SeriesNIDA research monograph -- 66, DHHS publication -- no. (ADM) 86-1444
ContributionsBraude, Monique C, Chao, Helen M, National Institute on Drug Abuse
The Physical Object
Paginationvii, 117 p. :
Number of Pages117
ID Numbers
Open LibraryOL14275790M

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Genetic and biological markers in drug abuse and alcoholism. Rockville, Md.: Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, (DLC) (OCoLC) Material Type:   Genetic and Biological Markers in Drug Abuse and Alcoholism: A Summary Warren W. Nichols, M.D., Ph.D. The workshop on "Genetic and Biological Markers in Drug Abuse and Alcoholism" reported in this monograph was jointly sponsored by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It 1. NIDA Res Monogr. ; Genetic and biological markers in alcoholism and drug abuse. Schuckit MA. PMID: [PubMed - indexed for MEDLINE] 1. NIDA Res Monogr. ; Genetic and biological markers in drug abuse and alcoholism. [No authors listed] PMID: [PubMed - indexed for MEDLINE]

  Genetic Epidemiology of AOD Dependence. Alcohol dependence frequently co- occurs with dependence on illicit drugs (Hasin et al. ). Both alco-hol use disorders (i.e., alcohol abuse and alcohol dependence) and drug use disorders (drug abuse and drug dependence) are influenced by several factors. For example, family, twin, and adoption studies. 1 Evidence of genetic predisposition to alcoholic cirrhosis and psychosis: twin concordances for alcoholism and its biological end points by zygosity among male veterans. Alcoholism: Clinical and Experimental Research 5, –   Drugs of abuse, including opioids, act on the brain’s reward system, a system that transfers signals primarily via a molecule (neurotransmitter) called dopamine. The function of this system is affected by genetic and environmental factors. For example, a recent study published in the scientific journal PNAS revealed one of those genetic Biological models of addiction emphasize the importance of genetics and the biological forces of nature. These theories suggest that brain chemistry, brain structure, and genetic abnormalities cause human behavior. Many of these models have not been tested or applied to every specific type of ://

1. Alcoholism causes changes to the brain's natural balance (homeostasis). 2. Alcoholism alters brain chemistry. 3. Alcoholism changes the brain's communication patterns. 4. Alcoholism causes changes to brain structures and their functioning. The addictions topic center explains these ways that addiction affects the brain in much greater ://?type=doc&id=&cn=   alcoholism, such as genetic differences in several neurotransmitters, including beta-endorphin and gamma-aminobutryic acid (GABA). KEY WORDS:screening and diagnostic method for AOD (alcohol and other drug) use; pattern of AOD use; alcohol-related biological markers; alcohol-related biochemical markers; alcohol-related genetic markers T For alcoholism a number of possible neurochemical and neurophysiological trait markers including the monoaminoxidase-B-activity in platelets, activity of adenylatcyclase, endocrine markers (Cortisol, ACTH, prolactin), dopamin-beta-hydroxylase, evoked potentials (P ) and ADH/ALDH genotypes have been proposed, but none of these markers has Am J Drug Alcohol Abuse – PubMed CrossRef Google Scholar Chick J, Kreitman N, Plant M () Mean cell volume and gammaglutamyltranspeptidase as markers of drinking in working men. Lancet i: – CrossRef Google Scholar